Grounding the fundamental advances of O1 to O4 in concrete epidemic related scenarios. We aim to go all the way from data collection; through modeling to evaluation with policy makers and citizens to make sure that the results of the project can have an impact in real life policies. Success Criteria: Models and computational tools validated on concrete use cases. Publications in epidemiology, medicine and public health journals. Adoption of the methods and tools by agencies and stakeholders for the analysis of real world use cases.